The more positive mood -- helped by a strong batch of US manufacturing data -- saw safe haven assets fall, with gold tumbling further from its record high above $1,900 and the yen weakening.
Regional firms with links to Apple slipped while its rivals rose after Steve Jobs announced his resignation of the US computer giant on Wednesday.
Tokyo closed 1.54 per cent, or 132.75 points, higher at 8,772.36 while Seoul rose 0.56 per cent, or 9.80 points, to 1,764.58 and Sydney added 0.98 per cent, or 45.2 points, to 4,212.8.
Taipei fell 1.23 per cent, or 92.06 points, to 7,410.87 while in the afternoon Hong Kong was 1.07 per cent higher and Shanghai jumped 2.32 per cent.
Traders took their cue from a third straight day of gains on Wall Street, where sentiment was boosted by data from the US Commerce Department showing new orders for durable goods rebounding 4.0 per cent in July from June, suggesting manufacturing growth could pick up in the coming months.
Markets were also buoyant as they awaited Bernanke's speech on Friday, which will be closely watched for signs of whether he endorses a further loosening of monetary policy to boost the world's leading economy.
Last year, during a speech at the same annual conference he hinted that the Fed might launch a second round of quantitative easing -- essentially, injecting fresh money into the economy in a bid to pump up growth. The Fed later carried through on the policy, fuelling a months-long stock surge.
On Wednesday the Dow rallied 1.29 per cent, the S&P 500 rose 1.31 per cent and the Nasdaq added 0.88 per cent.
The upbeat sentiment sent the price of gold tumbling in London, where it bottomed out at around $1,760 an ounce just days after it hit a record high $1,913.
The precious metal opened in Hong Kong at $1,763.00-$1,764.00 an ounce.
On currency markets the yen was slightly down from the previous day's highs.
The dollar rose to 77.11 yen in Tokyo morning trade from 76.97 yen in New York late Wednesday. It had been at 76.64 in Asia Wednesday.
Against the Japanese currency the euro edged up to 111.18 yen from 110.97 in New York Wednesday and 110.49 in Asia.
The euro bought $1.4415, just up from $1.4413 in New York.
However, despite the brighter data Kazuhiro Takahashi, general manager of investment strategy and research at Daiwa Securities in Japan, offered a note of caution.
"The three-day advance in US stocks is prompting bargain-hunting and short-covering, but overall sentiment still leans towards pessimism and trading will likely continue to be volatile going into next week," he told Dow Jones Newswires.
In the technology sector Apple-reliant shares were lower after Jobs -- considered the soul of the firm -- said he would resign as the firm's CEO.
Shares in the maker of the iPhone and iPad tumbled 5.3 per cent in after-hours US trade.
Taiwan component supplier Hon Hai, the parent company of Foxconn which assembles Apple's popular gadgets, shed 4.63 per cent.
However, Apple rivals rose, with HTC gaining 2.7 per cent in Taipei and in Seoul Samsung Electronics rose three per cent while LG Electronics, the world's third-biggest mobile phone maker, climbed four per cent.
Oil continued to edge back up as rebels and pro-government forces continued to battle it out in the Libyan capital of Tripoli.
Brent North Sea crude for October delivery was 10 cents up at $110.25. The contract had tumbled this week as it looked like the six-month battle for Libya was drawing to a close, which would allow oil to flow again.
New York's main contract, West Texas Intermediate light sweet crude for October delivery fell nine cents to $85.07 a barrel.
In other markets:
-- Manila closed 0.54 per cent, or 23.76 points, lower at 4,342.69.
Lepanto Mining shed 10 per cent to 1.6 pesos and San Miguel was unchanged at 124 pesos.
-- Wellington closed up 0.43 per cent or 14.06 points at 3,301.58.
Air New Zealand fell 1.8 per cent to NZ$1.09 after posting a 45 per cent fall in adjusted full year earnings, while Fletcher Building was unchanged at NZ$7.85 and Telecom Corp. rose 0.7 per cent to NZ$2.72.
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