The market found further support in hopes for a positive outcome to ongoing Greek debt talks and better-than-expected manufacturing figures in the eurozone.
New York's main contract, West Texas Intermediate crude for delivery in March, gained 11 cents to $98.59 a barrel.
Brent North Sea crude for March delivery advanced $1.23 to $112.21 a barrel in London late afternoon deals.
"The rise has been prompted by a mixture of things. The Iranian situation, particularly with the threat of additional US sanctions and reduced output, is still an issue," said analyst Tom Pering at British energy consultancy Inenco.
"The good news on increased manufacturing production in China has been tempered slightly by (a fall) in demand for exports.
"However, oil prices (also) rose on falling output in Sudan due to the transition dispute between South and North Sudan."
Talks between Iranian officials and a delegation from the UN atomic watchdog wrapped up late on Tuesday with no sign of any breakthrough over Tehran's nuclear programme, media reported.
The United States and the European Union have been piling severe economic sanctions on Iran in the past three months to pressure it to halt its nuclear activities, which they claim is aimed at building an atomic bomb.
On the back of an embargo on Iranian oil by the EU last week, US lawmakers on Tuesday unveiled proposals for fresh sanctions on Tehran.
Iran, which maintains that its nuclear programme is for peaceful purposes, has threatened to retaliate, possibly by closing the strategic Strait of Hormuz at the entrance to the Gulf.
The chief UN nuclear inspector returned from a visit to Tehran saying there was still "a lot of work" to do, with Iran's foreign minister insisting that the team did not visit any atomic sites.
Traders were also closely watching the situation in South Sudan, which has nearly completed a drastic shutdown of its oil production -- the fledging nation's top revenue resource -- over a revenue sharing dispute with Sudan.
South Sudan has accused Khartoum of stealing $815 million of its crude.
UN chief Ban Ki-moon said Sunday that tensions between the two countries and the oil row had become a major threat to regional peace and security.
South Sudan seceded peacefully from Sudan last July after decades of war but both countries have since repeatedly exchanged allegations that each backs proxy rebel forces against the other.
Aside from supply worries, oil prices also rose on Wednesday after official data showed that Chinese manufacturing activity improved in January despite weaker demand for exports.
The official purchasing managers index (PMI) rose to 50.5 in January from 50.3 in December, the China Federation of Logistics and Purchasing said in a statement.
Manufacturing expanded for the second month, after contracting for the first time in 33 months in November, when the PMI stood at 49.
A reading above 50 indicates the sector is expanding while a reading below 50 suggests a contraction. The data raised hopes that the world's second-largest economy is heading for a soft landing.
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